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Regulatory statusPHASE 3
MechanismTriple GIP / GLP-1 / glucagon receptor agonist
DeveloperEli Lilly
FormLyophilized powder · 10mg, 30mg, 60mg, 100mg
CAS2381089-83-2
Purity docsBatch-matched COA available on request — ask us.
Ships fromOntario, Canada
Intended useLaboratory research only. Not for human consumption.

About this compound

Retatrutide adds glucagon receptor agonism to the dual incretin backbone — recruiting energy expenditure alongside appetite regulation. Its phase 2 readout in the New England Journal of Medicine posted the largest mean weight reduction ever reported in an obesity trial at the time. Phase 3 (TRIUMPH) is underway.

Storage & handling

Lyophilized vials: keep sealed, dry, and away from light and heat. Refrigeration at 2–8°C is the best default; −20°C for long-term storage. After reconstitution: refrigerate at 2–8°C and use promptly — no beyond-use date is validated.

RETATRUTIDE

Retatrutide

In plain English: An experimental medicine that works three ways at once — in late-stage testing, not approved anywhere yet.

Three receptors, one molecule. The most ambitious incretin in development.

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From $37 CAD per vial

$15 flat shipping Canada-wide · free over $200

24.2%
Headline trial result.
mean weight loss at 48 weeks (phase 2, 12 mg weekly — NEJM 2023). Figures are mean change in the cited trial population — context in the science guide.
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